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Transformative Technologies 2010 nominees: Enzyme platforms

| June 7, 2010

Nominations: Enzyme technologies
To vote in Transformative Technologies 2010, visit here.

Codexis has received up to a $4.7 million grant from the U.S. Department of Energy for development of technology to remove CO2 from coal-fired power plant emissions using biocatalysts. The grant supports development of biocatalysts for more efficient carbon capture from coal-fired power plants. The technology is based on customized carbonic anhydrase biocatalysts that have the potential to enable cost effective, energy efficient capture of carbon dioxide. Codexis is developing this technology in collaboration with CO2 Solution Inc., based in Quebec, Canada.

In December, Dyadic International published an in-depth description of its Chrysosporium lucknowense (C1) fungus platform, in the Journal of Cereal Science. The article highlights the natural ability of the fungus to produce neutral cellulases, as well as the discovery of hemicellulase and esterase- encoding genes in the fungus. “All these enzymes were found to be active towards arabinoxylans, demonstrating the high potential of C1 as a producer of hemicellulolytic enzymes,” the article summary said.

Genencor announced the introduction of Accellerase DUET, featuring a 300 percent + increase in enzyme yields. With improved overall hemicellulase activity, Accellerase  DUET builds on the advances in beta-glucosidase and cellulase activity previously made by Accellerase 1500. These additional improvements allow Accellerase DUET to achieve higher sugar and biofuel yields, often at 3-fold lower dosing, and to be feedstock- and pretreatment- flexible.


Cellic CTec can provide cellulosic ethanol plants with up to a 2X enzyme dose reduction. A typical 55 MGY plant only needs to receive enzyme deliveries twice a week – freeing up capital costs and bringing affordable cellulosic ethanol into reach.

University of York project
Wood-eating gribble for low-cost biofuel. A project at the University of York to use enzymes produced by the wood-eating sea gribble (that causes wood rot in ships) to produce ethanol from wood waste.

Louisiana Tech enzyme project

Nanotechnology for cheaper biofuel. A project at Louisiana Tech University to immobilize and re-use enzymes.

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