JBEI develops workflow method to study biofuel production on microbial hosts

In California, researchers at the U.S. Department of Energy (DOE)’s Joint BioEnergy Institute (JBEI) in collaboration with researchers at the University of California, San Diego, have developed a workflow that integrates various omics data and genome-scale models to study the effects of biofuel production in a microbial host.

The development of omics technologies, such as metabolomics and proteomics, and systems biology have dramatically enhanced our ability to understand biological phenomena. Nevertheless the interpretation of large omics data into meaningful ‘knowledge’ as well as the understanding of complex metabolic interactions in engineered microbes remains challenging. This new open-source workflow which integrates various omics data and genome-scale models drives the transition from vision to conception of a designed working phenotype.