Purdue researchers develop engineered proteins to improve biomanufacturing

In Indiana, Purdue University researchers have developed a series of engineered proteins that could improve biomanufacturing processes for the production of biofuels, pharmaceuticals and commodity chemicals.

The buildup of toxic materials during the production process can damage cell health and typically lowers the overall amount of product that is made. Few tools are available to broadly address this issue.

The regulators are easily tailored to different biomanufacturing processes by selecting an appropriate transition setpoint for a given production pathway. They provide a generic tunable platform with clear design rules that can be developed for any process. Current approaches are product-specific and difficult to adapt.