University of Minnesota researchers make it possible to mutate a single gene at a time

May 13, 2020 |

In Minnesota, University of Minnesota researchers have now developed a tool that makes it possible to mutate a single gene at a time—opening the door not only to a better understanding of evolution, but also better ways to modify the genes of microbes to give them the ability to mass-produce molecules, such as biofuel-generating enzymes, for human use.

The approach—called Experimental Designed Genic Evolution, or EDGE—makes it possible to mutate a single, specific gene in E. coli bacteria without altering others. The study was published recently in PLOS ONE.

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Category: Research

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