Gingko BioWorks, Impossible Foods, Calysta, Bolt Threads, Zymergen take top slots in The 40 Hottest Emerging Companies in the Advanced Bioeconomy 2017-18

October 17, 2017 |

Ginkgo BioWorks took the #1 spot in the 2017-18 “40 Hottest Emerging Companies in the Advanced Bioeconomy” rankings, published today in The Digest and Nuu, the world’s most widely-read advanced bioeconomy dailies. It is the first time for Ginkgo at the top of the list, and the first time each of the others reached the top five.

Ginkgo BioWorks (#1), Impossible Foods (#2), Calysta (#3), Bolt Threads (#4), Zymergen (#5), Arzeda (#6),Oberon Fuels (#7), POET-DSM (#8), Leaf Resources (#9), and NexSteppe (#10), composed the top 10.

Ranked #11 through #20 are Caribou Biosciences, Mango Materials, Beyond Meat, Comet Biorefining, Twist Bioscience, Altair Fuels, Perfect Day, Vertimass, Clara Foods and Celtic Renewables.

A record number of new companies

With a new generation of companies based in advanced nutrition and synthetic bilogy, a shift in global commodity prices, mergers and significant progress towards commercial-scale by many companies, 13 companies reached the Hot 40 for the first time in 2016. They are:

ISOThrive (#24), Memphis Meats (#25), Provivi (#26), Muse bio (#27), Sierra Energy (#28), Benson Hill Biosystems (#29), Global Algae Innovatinos (#31), Livink Ink (#34), Microvi Biotechnologies (#36), Consumer Physics (#37), Visolis (#38), Crop Intelligence (#39), and Pivot Bio (#40).

Silicon Valley dominates

Overall, 20 companies founded in the technology hotbed of Silicon Valley — and overwhelmingly, US-founded companies dominated this early-stage company rankings. 37 of the 40 were US companies.

The rankings recognize biotechnology innovation and achievement in fuels, biobased chemicals, nutrition, health, syntheric biology, and materials, and the Hot 40 specifically recognizes emerging companies founded in the past 10 years. Rankings are based on votes from an invited panel of distinguished international selectors.

The Miami, FL-based Digest  and Nuu serves more than 2.8 million unique readers and followers via the web, newsletters, social media and broadcast in every UN-recognized country. The rankings have been conducted annually since 2008.

The 40 Hottest Emerging Companies in the Advanced Bioeconomy for 2017-18 are:

1 Gingko BioWorks

2 Impossible Foods

3 Calysta

4 Bolt Threads

5 Zymergen

6 Arzeda

7 Oberon Fuels


9 Leaf Resources

10 NexSteppe

11 Caribou Biosciences

12 Mango Materials

13 Beyond Meat

14 Comet Biorefining

15 Twist Bioscience

16 Altair Fuels

17 Perfect Day

18 Vertimass

19 Clara Foods

20 Celtic Renewables

21 Ripple Foods

22 Industrial Microbes

23 RedRock Biofuels

24 ISOthrive

25 Memphis Meats

26 Provivi

27 MuseBio

28 Sierra Energy

29 Benson Hill Biosystems

30 Modern Meadow

31 Global Algae Innovations

32 Novvi

33 Sylvatex

34 Living Ink

35 PrecisionHawk

36 Microvi Biotechnologies

37 Consumer Physics

38 Visolis

39 Crop Enhancement

40 Pivot Bio


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