First patent issued on TAL effector technology

May 14, 2013 |

In Illinois, the Two Blades Foundation announced the issuance of a key patent for gene editing based on the use of TAL effectors. TAL effectors are naturally occurring proteins found in plant pathogenic bacteria that contain a novel repeat structure that binds to specific DNA sequences according to a simple cipher or ‘code’.

The discovery of this code enables researchers to target proteins to virtually any DNA sequence in a genome with accuracy and ease to delete, add, alter, or regulate genes with high precision. Two Blades has worked with the inventors to develop the technology and a comprehensive estate of patents.

This issued patent, U.S. Pat. No. 8,420,782, is directed to TAL effectors with endonuclease activity. The Foundation is a not-for-profit organization focused on the development and deployment of durable disease resistance for agriculture.

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